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TUhjnbcbe - 2021/2/27 13:47:00

SCI

13April

AttributableFailureofFirst-lineCancerTreatmentandIncrementalCostsAssociatedWithSmokingbyPatientsWithCancer

WarrenGW,CartmellKB,Garrett-MayerE,SalloumRG,CummingsKM.AttributableFailureofFirst-lineCancerTreatmentandIncrementalCostsAssociatedWithSmokingbyPatientsWithCancer.JAMANetwOpen;2:e

CorrespondingAuthor:

GrahamW.Warren,MD,PhD,DepartmentofRadiationOncology,MedicalUniversityofSouthCarolina,AshleyAve,MSC,Charleston,SC(warrengw

musc.edu).

IMPORTANCE重要性

Previousstudieshaveshownthatcontinuedsmokingamongpatientswithcancercanincreaseoverallandcancer-specificmortality,riskforsecondprimarycancer,andriskfortoxiceffectsofcancertreatment.Toourknowledge,therehavebeennoeffortstoestimateadditionalcostsforcancertreatmentattributedtosmoking.

先前研究表明,癌症患者继续吸烟会增加总体和癌症特异性死亡率、第二原发癌风险以及癌症治疗的毒性作用风险。据了解,尚未有关研究评估因吸烟而增加的癌症治疗费用。

OBJECTIVE目标

Tomodelattributableincrementalcostsofsubsequentcancertreatmentassociatedwithcontinuedsmokingbypatientswithcancer.

对癌症患者持续吸烟导致的癌症后续治疗成本的增加量建立模型。

设计、设置和参与者

Forthiseconomicevaluation,amodelwasdevelopedinusingdatafromaUSSurgeonGeneral’sreportthatconsideredexpectedfailureratesoffirst-linecancertreatmentinnonsmokingpatients,smokingprevalence,oddsratiooffirst-linecancertreatmentfailureattributedtosmoking

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